Research Progress of Exercise Therapy in Lipid Metabolism
DOI:
https://doi.org/10.58557/(ijeh).v4i2.226Keywords:
Hyperlipidemia, Aerobic Exercise, Resistance Training, Lipid Metabolism, Non-Pharmacological InterventionsAbstract
Persistent elevation of blood lipids promotes the accumulation of cholesterol in the vascular walls, leading to atherosclerosis, which is a key risk factor for serious cardiovascular and cerebrovascular diseases such as coronary heart disease and stroke. Hyperlipidemia is mainly classified into two subtypes: primary and secondary. Its occurrence is influenced by multiple factors, including genetic predisposition, dietary habits, liver metabolism abnormalities, insulin resistance, and oxidative stress. Aerobic exercise has a significant positive impact on hyperlipidemia by promoting fat oxidation and reducing lipid parameters. Resistance training effectively improves lipid metabolism by increasing muscle mass and enhancing basal metabolic rate. Although several sports medicine organizations worldwide have advocated the use of exercise prescriptions to prevent and treat chronic diseases, this approach has not been widely and effectively applied in the prevention and treatment of hyperlipidemia. This paper aims to review the pathogenesis of hyperlipidemia and explore the role of exercise in lipid regulation, advocating for the achievement of fat reduction goals through physical activity to provide a scientific basis for the treatment of hyperlipidemia
References
Augustine, J., Tarzia, B., Kasprowicz, A., & Heffernan, K. S. (2014). Effect of a single bout of resistance exercise on arterial stiffness following a high-fat meal. Int J Sports Med, 35(11), 894-899.
Bacchi, E., Negri, C., Zanolin, M. E., Milanese, C., Faccioli, N., Trombetta, M., Zoppini, G., Cevese, A., Bonadonna, R. C., Schena, F., Bonora, E., Lanza, M., & Moghetti, P. (2012). Metabolic effects of aerobic training and resistance training in type 2 diabetic subjects: a randomized controlled trial (the RAED2 study). Diabetes Care, 35(4), 676-682.
Bragg, D. A., & Walling, A. (2015). Metabolic Syndrome: Hyperlipidemia. FP Essent, 435, 17-23.
Chang Feng, Shi Jinyi, Wang Lu, et al. (2019). Analysis of Fall Risk Index in Elderly People with Different Exercise Methods and Different Chronic Diseases. Chinese Journal of Sports Medicine, 38(06), 441-448.
Dou Yanli, & Chen Jinao. (2022). Effects of Ganoderma Lucidum Polysaccharides Combined with Aerobic Exercise on Lipid-Lowering and Antioxidant Levels in Hyperlipidemic Mice. Science and Technology of Food Industry, 43(09), 372-380.
Gavin, C., Sigal, R. J., Cousins, M., Menard, M. L., Atkinson, M., Khandwala, F., Kenny, G. P., Proctor, S., Ooi, T. C., Diabetes, A., & Resistance Exercise trial, i. (2010). Resistance exercise but not aerobic exercise lowers remnant-like lipoprotein particle cholesterol in type 2 diabetes: a randomized controlled trial. Atherosclerosis, 213(2), 552-557.
Kacerovsky-Bielesz, G., Kacerovsky, M., Chmelik, M., Farukuoye, M., Ling, C., Pokan, R., Tschan, H., Szendroedi, J., Schmid, A. I., Gruber, S., Herder, C., Wolzt, M., Moser, E., Pacini, G., Smekal, G., Groop, L., & Roden, M. (2012). A single nucleotide polymorphism associates with the response of muscle ATP synthesis to long-term exercise training in relatives of type 2 diabetic humans. Diabetes Care, 35(2), 350-357.
Karr, S. (2017). Epidemiology and management of hyperlipidemia. Am J Manag Care, 23(9 Suppl), S139-S148.
Khalil, Y. A., Rabes, J. P., Boileau, C., & Varret, M. (2021). APOE gene variants in primary dyslipidemia. Atherosclerosis, 328, 11-22.
Kraus, W. E., Houmard, J. A., Duscha, B. D., Knetzger, K. J., Wharton, M. B., McCartney, J. S., Bales, C. W., Henes, S., Samsa, G. P., Otvos, J. D., Kulkarni, K. R., & Slentz, C. A. (2002). Effects of the amount and intensity of exercise on plasma lipoproteins. N Engl J Med, 347(19), 1483-1492.
Li, D., Zhang, J., & Liu, Q. (2022). Brain cell type-specific cholesterol metabolism and implications for learning and memory. Trends Neurosci, 45(5), 401-414.
Liu Yi, & Hu Jun. (2018). Preliminary Study on the Intervention of Table Tennis on Diabetic Patients with Hyperlipidemia. Journal of Lanzhou University of Arts and Science (Natural Science Edition), 32(03), 87-89.
Navar-Boggan, A. M., Peterson, E. D., D'Agostino, R. B., Sr., Neely, B., Sniderman, A. D., & Pencina, M. J. (2015). Hyperlipidemia in early adulthood increases long-term risk of coronary heart disease. Circulation, 131(5), 451-458.
Qiu Dan, He Hui, Chen Xiaoke, et al. (2023). Effects of Long-Term Swimming and Running on Vascular Endothelial Function and Hemodynamics in Middle-Aged Men. Chinese Journal of Rehabilitation Medicine, 38(09), 1239-1246.
Schulze, P. C., Drosatos, K., & Goldberg, I. J. (2016). Lipid Use and Misuse by the Heart. Circ Res, 118(11), 1736-1751. https://doi.org/10.1161/CIRCRESAHA.116.306842
Shaw, I., & Shaw, B. S. (2006). Consequence of resistance training on body composition and coronary artery disease risk. Cardiovasc J S Afr, 17(3), 111-116.
Thompson, A., Carroll, K., L, A. I., Floege, J., Perkovic, V., Boyer-Suavet, S., R, W. M., J, I. S., Barratt, J., Cattran, D. C., B, S. G., Kausz, A., A, W. M., Reich, H. N., B, H. R., West, M., & Nachman, P. H. (2019). Proteinuria Reduction as a Surrogate End Point in Trials of IgA Nephropathy. Clin J Am Soc Nephrol, 14(3), 469-481.
Wang J. (2018). The Effect of Swimming on Reducing Hypertension and Hyperlipidemia in Middle-aged and Elderly People. Chinese Sports Coach , 26(04), 76-78.
Yang, Y., & Chan, L. (2016). Monogenic Diabetes: What It Teaches Us on the Common Forms of Type 1 and Type 2 Diabetes. Endocr Rev, 37(3), 190-222.
Zhang Lijuan, Zhang Yanlong, & Ma Zhijun. (2013). Effects of Resistance Exercise on Blood Lipids in Middle-Aged and Elderly Obese Women. Contemporary Sports Technology, 3(08), 23+128.
Zhang Yong, & Li Zhijun. (2013). Study on Fat Oxidation Kinetics and Maximum Fat Oxidation Intensity in Trained and Untrained Individuals. Journal of Sports Science, 33(02), 61-68.
Zhao S. (2022). Meta-Analysis of the Effect of Moderate-Intensity Aerobic Exercise on Lipid Levels in Patients with Hyperlipidemia—Evidence from Randomized Controlled Trials. Journal of Wuhan Sports University , 56(03), 79-85.
Zhao Zhigang, Zhou Fang, & Wang Lei. (2016). Effects of Dietary Control Combined with 12 Weeks of Different Intensity Resistance Training on Postprandial Blood Lipid Levels in Middle-Aged Women with Hyperlipidemia. Chinese Journal of Rehabilitation Medicine, 31(02), 194-198.
Zhao, S., Zhong, J., Sun, C., & Zhang, J. (2021). Effects of aerobic exercise on TC, HDL-C, LDL-C and TG in patients with hyperlipidemia: A protocol of systematic review and meta-analysis. Medicine (Baltimore), 100(10), e25103.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Wu Yuwei
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
